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Home » Healthcare » Biotechnology » HBI-2021015
  • Global CRISPR Market Insights, Opportunity, Analysis, Market Shares And Forecast 2017 – 2023

  • Publish: May 2017 | Report Code: HBI-2021015

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CRISPR (Clustered Regularly Interspaced Short Palindromic Repeat) is an RNA guided gene editing system that uses bacterially derived protein (Cas9) and a synthetic guided RNA to introduce a double strand brake at a particular location within the genome. Through this method, bacteria capture short sequences of nucleic acid from invading pathogens and combine them in CRISPR loci amidst the repeats. Small RNA’s produced by transcription of CRISPR loci, guides a set of bacterial endonucleases to split the genomes of invading pathogens. This system has been adopted as a powerful technique enabling genome editing into the mainstream. The Global CRISPR Market is expected to have a CAGR of 36.2%% for the forecast period of 2016-2023.Technological advancement is the key driver for global CRISPR market. Moreover, rise in the drug discovery market, increasing demand for synthetic genes, rising age related genetic disorders and rise in the healthcare research & development budgets are also fuelling the global CRISPR market. However, limited awareness and ethical issues are restraining factors of the global CRISPR market.

The gene editing technology has grown significantly in the last decade as the gene editing tools have become more accessible and cost effective which has enabled a thorough understanding of human genome. CRISPR (clustered regularly interspaced short palindromic repeats) is a new gene editing tool which has opened new doors for gene editing. This technology allows researchers to perform microsurgery on genes, precisely and easily, changing a DNA sequence at exact locations on a chromosome. CRISPR market is expected to grow due to drivers such as increased R&D expenditure on biotechnology, backed by venture capitals, increasing age related genetic disorders, increasing private and government expenditure on genetic research, high prevalence rate of genetic birth disorders and high demand of synthetic genes. Several factors such as limited awareness and little presence in emerging markets are restraints in the path of growth of the market.

 

Source: OBRC Analysis.

Increasing demand for synthetic genes- with the discovery of the CRISPR-CAS9 system from streptococcus pyogenes, genome editing has been revolutionized. CRISPR (clustered regularly interspaced short palindromic repeat) is an RNA guided gene editing system that uses bacterially derived protein (Cas9) and a synthetic guided RNA to introduce a double strand brake at a particular location within the genome. Through this method, bacteria capture short sequences of nucleic acid from invading pathogens and combine them in CRISPR loci amidst the repeats. Small RNA’s which are produced by transcription of CRISPR loci, guides a set of bacterial endonucleases to split the genomes of invading pathogens. This system has been adopted as a powerful technique enabling genome editing into the mainstream.

Gene editing is done by transfecting a cell with Cas9 protein along with guided RNA (Grna) that directs hybridization with its matching genomic sequence. CRISPR is good particularly for the efficient generation of complete knockout of genes on multiple alleles. 

The report on global CRISPR market includes segmentation on the basis of application and end-user.

Application is sub segmented into:

  • Genome Editing
  • Genetic Engineering
  • Grna Database/Gene Library
  • Crispr Plasmid
  • Human Stem Cells
  • Genetically Modified Organisms/Crops
  • Cell Line Engineering








End-user is sub segmented into:

  • Biotechnology Companies
  • Pharmaceutical Companies
  • Academic Institutes
  • Research and Development Institutes





The revenue for the above application and end-user segments are specific to global CRISPR market. However, the total revenue of these application and end-user in general has been excluded from the scope of the report.

The global CRISPR market report is geographically segmented into:

  • North America (U.S. & Canada)
  • Asia Pacific (China, India, Japan, RoAPAC)
  • Europe (UK, France, Germany, RoE)
  • Rest of World





The Global CRISPR market is segmented on the basis of application and end users. On the basis of application the market is further segmented into Genome Editing, Genetic engineering, gRNA Database/Gene Library, CRISPR Plasmid and vectors so on. CRISPR Plasmid is the highest growing segment due to high demand among scientists and researchers. By end user, the market is segmented into Biotechnology companies, Pharmaceutical companies, Academic and research Institutes, Research and development institutes, Competitive Intelligence, Merger and Acquisitions and Innovation. In end user, academic and research is the highest growing segment due to high level of R&D into genome process, development of new drugs and development of genetically modified organisms and drugs.

The geography analysis consists of North America (US, Canada), Europe (United Kingdom, France, Germany, Spain, Italy), Asia Pacific (India, China, Japan) and Rest of the world. North America was the largest geographical market (2015) in CRISPR due to high level of academies and research based in region. Asia-Pacific is expected to grow at the fastest rate in forecast period due to increase in number of contract research organization and emergence of drug discovery.

The major market players of the global CRISPR market are:

  • CARIBOU BIOSCIENCES
  • CELLECTIS
  • CRISPR THERAPEUTICS
  • EDITAS MEDICINE
  • HORIZON DISCOVERY PLC
  • OTHERS







These companies use various strategies such as merger & acquisition, collaboration, partnership and product launch. Whereas, merger & acquisition is the key strategy adopted by the companies in the CRISPR market.

For Example; On October 8, 2015, DuPont and Caribou Bioscience entered into a multiyear research collaboration to develop the genome editing technology platform. Caribou is a leading CRISPR Cas technology developer for genome editing. As per the agreement, the companies provided license to each other for the development of their corresponding exclusive portfolios. However, the amount involved in the agreement was not disclosed by both the companies. The cross license permitted Caribou to advance and exploit CRISPR-Cas technology for the new product development in field such as diagnostics, human and animal therapeutics, research tools, agriculture segments and industrial biotechnology. DuPont license is exclusively given by Vilnius University for the Cas9-medicated genome editing, an intellectual property right owned by Vilnius University.

The report covers detailed analysis of companies which comprises of overview, SCOT analysis, product portfolio, strategic initiative, strategic analysis, competitive landscape and market share analysis for global CRISPR market.

Key reason to buy the report:

  • The report includes market estimation, forecast and analysis for the year 2016-2023
  • Report includes detailed analysis of different segments such as end-user and applications of CRISPR.
  • Identify and understand the strengths, opportunities, challenges and threat of the CRISPR market.
  • Covers details analysis of Porters 5 force model and other strategic models and also covers revenues, market share analysis, and competitive landscape analysis of major players of voice communication segment market.
  • Detailed analysis of various regulatory policies which affect the global CRISPR market.






How we are different from others:

At Occams we provide an extensive portfolio which is comprehensive market analysis along with the market size, market share, and market segmentations. Our report on global CRISPR market offers detailed analysis of strategic models such as investment vs. adoption model, see saw analysis and others strategic models. Also, the report contains the detailed analysis of application, adoption scenario and decision support for each segment. The report discusses competitive landscape of the CRISPR market, with giving extensive SCOT analysisof key companies. 

Key findings of the global CRISPR market:

  • North America held highest revenue share in 2016.
  • CRISPR Plasmid is the fastest growing segment due to high demand among scientists and researchers
  • Acquisition is the key strategy adopted by players of CRISPR market.
  • In end user, the academic and research has the highest growth rate.
1.    EXECUTIVE SUMMARY
1.1.    ESTIMATION METHODOLOGY
    
2.    MARKET OVERVIEW
2.1.    CRISPR- INTRODUCTION
2.2.    VALUE CHAIN ANALYSIS
2.3.    KEY BUYING CRITERIA
2.4.    RESEARCH AND DEVELOPMENT
2.4.1.    PATENT ANALYSIS
2.5.    CRISPR VS. CONVENTIONAL GENE EDITING TOOLS
2.5.1.    TALEN
2.5.2.    ZFN
2.6.    CRISPR: NOVEL INITIATIVES
2.6.1.    CRISPR CAS9 TECHNOLOGY
2.6.2.    CRISPR AS A GENE EDITING TOOL TO TREAT GENETIC DISORDERS
2.6.2.1.    GENE SURGERY
2.6.3.    CRISP AS A GENE EDITING TOOL IN DRUG DEVELOPMENT
2.7.    STRATEGIC RECOMMENDATION AND CONCLUSION
    
3.    SECTOR ANALYSIS
3.1.    GENE EDITING MARKET
    
4.    MARKET DETERMINANTS
4.1.    DRIVERS
4.1.1.    RISE IN DRUG DISCOVERY MARKET
4.1.2.    DEMAND FOR SYNTHETIC GENES
4.1.3.    HIGH PREVALENCE OF GENETIC BIRTH DISORDERS
4.1.4.    AGE RELATED GENETIC DISORDERS
4.1.5.    RISE IN THE HEALTHCARE RESEARCH AND DEVELOPMENT BUDGETS
4.1.6.    VENTURE CAPITAL
4.1.7.    GLOBAL INCREASE IN LIFE STYLE ORIENTED DISEASES & FATALITIES
4.1.8.    GMOS INCREASE CROP YIELDS AND PROMOTE EFFICIENT LAND USE
4.2.    RESTRAINTS
4.2.1.    ETHICAL ISSUES RELATED TO MISUSE OF CRISPR GENE EDITING TOOL
4.2.2.    LIMITED AWARENESS
4.2.3.    LIMITED PRESENCE IN EMERGING MARKETS
4.3.    OPPORTUNITIES
4.3.1.    CRISPR GENE EDITING CAN OPEN THE MARKET FOR GENE SURGERY.
4.3.2.    EMERGING CONTRACT RESEARCH MARKET IN ASIA
4.4.    CHALLENGES
4.4.1.    PATENT INFRINGEMENT
4.4.2.    PRESENCE OF ALTERNATIVE GENE EDITING TOOLS
    
5.    MARKET SEGMENTATION
5.1.    BY APPLICATION
5.1.1.    GENOME EDITING
5.1.2.    GENETIC ENGINEERING
5.1.3.    GRNA DATABASE/GENE LIBRARY
5.1.4.    CRISPR PLASMID
5.1.5.    HUMAN STEM CELLS
5.1.6.    GENETICALLY MODIFIED ORGANISMS/CROPS
5.1.7.    CELL LINE ENGINEERING
5.2.    BY END USER
5.2.1.    BIOTECHNOLOGY COMPANIES
5.2.2.    PHARMACEUTICAL COMPANIES
5.2.3.    ACADEMIC INSTITUTES
5.2.4.    RESEARCH AND DEVELOPMENT INSTITUTES
5.3.    COMPETITIVE INTELLIGENCE
5.3.1.    MERGER AND ACQUISITIONS
5.3.2.    INNOVATION
5.3.3.    VENTURE CAPITAL FUNDING
    
6.    GEOGRAPHICAL ANALYSIS
6.1.    NORTH AMERICA
6.1.1.    UNITED STATES
6.1.2.    CANADA
6.1.3.    RONA (REST OF NORTH AMERICA)
6.2.    EUROPE
6.2.1.    UNITED KINGDOM
6.2.2.    FRANCE
6.2.3.    GERMANY
6.2.4.    SPAIN
6.2.5.    ITALY
6.2.6.    ROE (REST OF EUROPE)
6.3.    ASIA PACIFIC
6.3.1.    CHINA
6.3.2.    JAPAN
6.3.3.    INDIA
6.4.    REST OF THE WORLD
6.5.    MIDDLE EAST AND AFRICA
6.5.1.    LATIN AMERICA
6.5.2.    BRAZIL
    
7.    COMPANY PROFILING
7.1.    THERMO FISHER SCIENTIFIC
7.2.    EDITAS MEDICINE
7.3.    CARIBOU BIOSCIENCES
7.4.    CRISPR THERAPEUTICS
7.5.    INTELLIA THERAPEUTICS, INC.
7.6.    CELLECTIS
7.7.    HORIZON DISCOVERY PLC
7.8.    SIGMA ALDRICH
7.9.    PRECISION BIOSCIENCES
7.10.    GENSCRIPT
7.11.    SANGAMO BIOSCIENCES INC.
7.12.    LONZA GROUP LIMITED
7.13.    INTEGRATED DNA TECHNOLOGIES
7.14.    NEW ENGLAND BIOLABS
7.15.    OREGENE TECHNOLOGIES
7.16.    TRANSPOSGENBIOPHRAMACEUTICALS
    
    
LIST    
1    GLOBAL CRISPR MARKET BY END USERS 2014-2023 ($ MILLION)
2    COMPARISON BETWEEN CRISPR, ZFN AND TALENS
3    VARIOUS INITIATIVES AND POLICIES UNDER TAKEN BY THE GOVERNMENT IN HEALTHCARE SECTOR
4    RISING PUBLIC HEALTH AND LONG-TERM CARE EXPENDITURE OVER THE NEXT DECADES
5    MAJOR CONCERNS RELATED WITH THE GENETIC ENGINEERING
6    GLOBAL AREA OF GENETIC MODIFIED CROP IN 2013 AND 2014 BY COUNTRIES (MILLION HECTARES)
7    GLOBAL CRISPR MARKET BY BIOTECH FIRMS 2014-2023 ($ MILLION)
8    GLOBAL CRISPR MARKET BY PHARMA COMPANIES 2014-2023 ($ MILLION)
9    GLOBAL CRISPR MARKET BY ACADEMIC INSTITUTIONS 2014-2023 ($ MILLION)
10    GLOBAL CRISPR MARKET BY RESEARCH FOUNDATION 2014-2023 ($ MILLION)
11    EUROPE CRISPR MARKET 2014-2023 ($ MILLION)
12    ASIA PACIFIC CRISPR MARKET 2014-2023 ($ MILLION)
13    GOVERNMENT ENTITIES ENTITLED FOR RESEARCH AND RESTRICTIONS UNDER TYPE 2 USAGE
    
FIGURES LIST    
1    NUMBER OF SCIENTIFIC PAPERS ON CRISPR (2012-2015)
2    GLOBAL CRISPR MARKET 2014-2023 ($ MILLION)
3    VALUE CHAIN ANALYSIS OF CRISPR MARKET
4    PATENT BY END USER
5    CAUSES OF DEATHS DURING 2014, WORLDWIDE
6    FATALITIES INCREASING DUE TO LIFE STYLE ORIENTED DISEASES (IN THOUSAND)
7    TOP REASONS A COMPANY OUTSOURCES DRUG DISCOVERY PROJECTS TO CRO’S
8    GLOBAL CRISPR MARKET BY GENOME EDITING 2014-2023 ($ MILLION)
9    GLOBAL CRISPR MARKET BY GENETIC ENGINEERING 2014-2023 ($ MILLION)
10    GLOBAL CRISPR MARKET BY GRNA DATABASE/GENE LIBRARY 2014-2023 ($ MILLION)
11    GLOBAL CRISPR MARKET BY CRISPR PLASMID AND VECTORS 2014-2023 ($ MILLION)
12    GLOBAL CRISPR MARKET BY HUMAN STEM CELL 2014-2023 ($ MILLION)
13    GLOBAL CRISPR MARKET BY GENETICALLY MODIFIED ORGANISMS/CROPS2014-2023 ($ MILLION)
14    GLOBAL CRISPR MARKET BY CELL LINE ENGINEERING 2014-2023 ($ MILLION)
15    GLOBAL CELL LINE DEVELOPMENT MARKET SHARE BY REGION, 2014
16    GLOBAL CRISPR MARKET BY END USER MARKET 2014-2023 ($ MILLION)
17    GLOBAL CRISPR MARKET BY BIOTECH FIRMS 2014-2023 ($ MILLION)
18    LEADING VENTURE CAPITAL FINANCED BIOTECHNOLOGY COMPANIES IN SWITZERLAND IN 2014, BY INVESTED AMOUNT ($ MILLION)
19    GLOBAL CRISPR MARKET BY PHARMA COMPANIES 2014-2023 ($ MILLION)
20    LIST OF TOP UNIVERSITIES AROUND THE WORLD FOR GENETIC ENGINEERING, 2015
21    GLOBAL CRISPR MARKET BY ACADEMIC INSTITUTIONS 2014-2023 ($ MILLION)
22    GLOBAL CRISPR MARKET BY RESEARCH FOUNDATION 2014-2023 ($ MILLION)
23    GLOBAL CRISPR MARKET COMPANIES SHARE 2014
24    GLOBAL CRISPR MARKET SHARE BY REGION IN 2015
25    NORTH AMERICA CRISPR MARKET 2014-2023 ($ MILLION)
26    ADOPTION OF GMO CROPS IN THE US IN 2014
27    NORTH AMERICA’S CRISPR MARKET SHARE IN 2015
28    GLOBAL PHARMACEUTICAL MARKET REVENUE DISTRIBUTION BY REGION IN 2014
29    US CRISPR MARKET 2014-2023 ($ MILLION)
30    REASONS FOR ADOPTING GENETICALLY ENGINEERED CROP (BT COTTON)
31    FUNDS ALLOCATED FOR RESEARCH ACTIVITIES IN BUDGET 2016
32    GM CROPS GROWN IN CANADA IN 2014
33    CANADA CRISPR MARKET 2014-2023 ($ MILLION)
34    RONA CRISPR MARKET 2014-2023 ($ MILLION)
35    EUROPE CRISPR MARKET 2014-2023 ($ MILLION)
36    UK CRISPR MARKET 2014-2023 ($ MILLION)
37    FRANCE CRISPR MARKET 2014-2023 ($ MILLION)
38    GERMANY CRISPR MARKET 2014-2023 ($ MILLION)
39    SPAIN CRISPR MARKET 2014-2023 ($ MILLION)
40    ITALY CRISPR MARKET 2014-2023 ($ MILLION)
41    REST OF EUROPE CRISPR MARKET 2014-2023 ($ MILLION)
42    CHINA CRISPR MARKET 2014-2023 ($ MILLION)
43    JAPAN CRISPR MARKET 2014-2023 ($ MILLION)
44    INDIA CRISP MARKET 2014-2023 ($ MILLION)
45    ROW CRISPR MARKET 2014-2023 ($ MILLION)
46    PHARMACEUTICAL MARKET SIZE FOR AFRICA ($ BILLION)
47    BRAZIL’S POSITION IN CULTIVATED GM CROP AREA

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